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King Tut’s DNA Paternity Test

August 7th, 2008 by Beta Panel

Even though the legendary Egyptian king has been dead for thousands of years, King Tutankhamun’s mummy is undergoing paternity tests to see if the mummified remains of two stillborn children found in his tomb are his offspring. According to a BBC online article, the British archaeologist who discovered King Tut’s tomb in 1922 found the fetuses then, but this is the first time scientists have attempted DNA paternity testing on the mummified tissue. Scientists will also compare the fetuses’ DNA to each other to determine if a sibling relationship exists, which will aid scientists in confirming both the fetuses’ paternity and maternity.

Scientists and scholars believe that the fetuses’ mother was King Tut’s only known wife, Ankhesenamum, daughter of the beautiful, legendary Queen Nefertiti. They hope that by identifying the relationship between the fetuses and King Tut they may eventually be able to locate Queen Nefertiti’s mummy, which has never been found.

King Tut ruled Egypt from 1333-1324 BC and rose to power around age 8 or 9. He died around a decade later and is believed to have had no surviving children. King Tut became famous around the world when his tomb was discovered by British explorer Howard Carter in 1922. Tut’s tomb was intact and contained immense amounts of gold and ebony treasures, as well as archeological finds like perfectly preserved bones and tissue of the king himself.

The DNA paternity tests will be performed at the Cairo School of Medicine.

DNA testing on hair of an … ape-man?

August 1st, 2008 by Beta Panel

According to a BBC online article published last week, scientists in the UK have examined the hairs from an unknown animal that some think may belong to the legendary Yeti, or ape-man, creature that has been known throughout Indian lore for years. According to many Indian villagers, legend has it that the 8-foot-tall “mande barung,” or “forest man,” lives deep in the Garo hills of Northeast India. Reported sightings of this half-man, half-ape creature over many generations have led many around the world to try to prove or disprove the yeti’s existence.

The scientists at Oxford Brookes University are using DNA testing and analysis to compare the strands of hair to several species of primates. They are also comparing these hairs, collected by a forester in 2003, to a hair sample collected by Sir Edmund Hillary in the early 1930s. So far, scientists have said the DNA analysis has been inconclusive, with no matches to existing species of animal so far.

While the legend of the yeti has sparked international debate, one thing is certain: DNA testing performed on hair strands can provide powerful scientific proof of a person or animal’s identity. In fact, scientists have been using hair to answer identity questions through DNA testing and analysis since the 1990s. DNA testing on hair is often used for identification purposes in forensic DNA tests, and can also be used to help determine biological relationships, like paternity.

August 1st, 2008 by Beta Panel

DNA-Tested Sandwich May Solve Robbery

July 22nd, 2008 by Beta Panel

A quote by a British Detective says it all when it comes to how DNA might help solve a recent mugging: “It’s not the brightest idea to leave your lunch at a crime scene,” Det. Con. Pete Wormley said.

According to a Mirror article a teenager apparently took an elderly woman’s purse and ran off, but not before leaving what police think is his half-eaten lunch behind in a cemetery near where the mugging took place.

Police and crime scene investigators are now testing the remnants of the lunch—specifically, a ham sandwich and potato chips—for any DNA evidence that could lead them to the robber.

It remains to be seen whether the DNA evidence on the ham sandwich will make up the meat of this case, or if other evidence will be needed to apprehend the munching mugger.

Extraction of Viking DNA from Skeletal Remains

July 18th, 2008 by Beta Panel

Scientists reported that they have successfully extracted “authentic” viking DNA from skeletal remains.

It is very difficult to extract a pure sample of ancient human DNA that is free of contamination from modern human sources. Ancient DNA that is intact is very hard to find, and is often in scarce amounts. The fact that modern human DNA is abundant in every step of the process, from excavation of remains to DNA analysis, further complicates the DNA extraction process—and this has caused many scientists to believe that it is virtually impossible to obtain uncontaminated ancient human DNA.

A pure sample is essential in order to properly analyze the DNA for migration patterns and origins of genetic diseases. Previous studies using ancient DNA have led to ill-formed conclusions that were later disproved due to evidence of contamination.

The scientist were able to achieve pure ancient DNA extracts by:

  1. Analyzing DNA from ten Viking Age subjects that at the time of sampling were untouched by humans for 1,000 years.
  2. Removing teeth from the subjects prior to handling by archaeologists and anthropologists using protective equipment.
  3. For comparison, removing an additional tooth after standard archaeological and anthropological handling.

All work was carried out in a “clean laboratory” dedicated solely to ancient DNA work. The scientists found that consistent results were obtained with the “unhandled” teeth and there was no indication of contamination, unlike the second tooth from which DNA was extracted after normal handling.

Using the pure ancient DNA, they were able to discover mitochondrial DNA patterns that are infrequent or have not been observed in modern Scandinavians.

DNA Used to Solve Gas Theft

July 10th, 2008 by Beta Panel

The media often tells instances in which DNA is used to solve violent or sex crimes, but a recent article from the United Kingdom explains how traces of DNA caught a thief in a different sort of crime.

With the rising cost of fuel around the world, an increasing number of people are resorting to theft to meet their fuel needs. However, Carl Anthony Little was not only caught stealing gasoline, but was reported to have then sold the stolen gas for a profit. British authorities say he committed 6 gas thefts in 6 days, stealing over $4,000 (£2,000) worth of diesel fuel in all.

Little was caught when he woke the driver of a parked load-carrying truck while he was siphoning diesel from the truck’s tank. As Little tried to get away, he left behind the equipment he used to siphon the fuel, and authorities were able to match Little to DNA left on the equipment.

Little is now on a 3-month curfew, and must also pay about $120 in fines. Prosecutors are also seeking additional punishment for each of Little’s 5 other alleged gas-stealing escapades.

Regarding his client and the charges at hand, Little’s defense attorney said, “This was a temporary misguided period in his life. He thought he could make a few pounds by stealing other people’s diesel. Clearly that was not the case.”

The DNA Science of Sweetness

July 2nd, 2008 by Beta Panel

Last week, the U.S. Department of Agriculture launched a $10 million project—funded by the candy company Mars Inc.— to analyze the complete cocoa genome. According to an Associated Press article, the goal of the project is to help identify and understand what DNA traits make certain cocoa trees susceptible to fungal diseases and draught, and could potentially save cocoa farmers up to $700 million in sick or dead trees annually.

However, in addition to saving cocoa trees and their farmers’ cash, scientists will use the opportunity to understand other genetic properties of the cocoa bean—including the genes that affect its taste properties. Mars Inc., the maker of M&Ms, Snickers and other famous chocolates, has said it will release the findings of the study to the public, including its competitors.

It seems that the uses for genome research are expanding at a rate sweeter than ever.

Paternity Tests at the Pub: King’s Descendants Drink Free

June 20th, 2008 by Beta Panel

According to a June 14 online article, male patrons were offered free DNA paternity tests at two pubs in New York and Ireland in an effort to identify descendents of Niall of the Nine Hostages, a 5th-century warlord and king. Any man that was proven to be related to Niall was eligible for free drinks and a free meal.

The Oxford, England, ancestral DNA testing company (affiliated with Oxford University) that is trying to identify more of Niall’s ancestors are able to do so by studying the tested men’s Y chromosome, which can be used to identify men that share a common male lineage. Niall—who’s name eventually became the source for the common Irish name O’Neill—had 12 sons, and could have had millions of descendants. In the U.S., researchers estimate that around 2 percent of Irish-American men could be descendants of the Irish King.

The researchers hope that by offering the DNA tests at the pubs, they can make “serious genetic research… less dusty and scientific,” one scientist said.

Beta Genetics’ sister company performs DNA tests similar to this one. DNA Diagnostics Center (DDC) can test two or men to see if they share the same Y chromosome, called Y-STR testing. This test can confirm whether or not two or more men descended from the same paternal line. For more information on Y-STR testing, please visit DDC’s resource page.

Primate Paternity Problems—Swiss Zoo Makes Interesting Discovery

June 4th, 2008 by Beta Panel

Zookeepers in Basel, Switzerland, made a shocking discovery when they analyzed DNA from a young gorilla as part of data it keeps on animals born in captivity.

A DNA test showed that young Chelewa was not fathered by 17-year-old gorilla Kisoro as zookeepers assumed. Within captive gorilla tribes, it has been known by scientists and zookeepers that only male gorillas 12 years or older have the “right” to mate with females in their tribe. But in the case of Chelewa, normal mating rituals seem to have been oddly overturned. The DNA test proved that a much younger male—9-year-old Viatu—had fathered Chelewa by mating with one of the tribe’s females.

In an AFP online article, zookeepers called the situation “almost unbelieveable,” and that by mating with a female at such a young age, Viatu had “broken all the rules that apply in gorilla communities.”

It seems young Viatu certainly has shaken up this zoo’s gorilla clan with his sneaky monkey business!

The Need for Speed: Danica Patrick’s DNA

May 27th, 2008 by Beta Panel

According to a USA Today article published online last week, Danica Patrick’s “need for speed” may be due in part to genes she inherited from her parents, who also participate heavily in “thrill” sports, especially snowmobile racing.

Danica Patrick became the first woman to win an IRL event in April and raced last weekend at the Indy 500, where a collision prevented her from finishing the race with only 29 laps remaining.

After studying people who participate in high-risk sports and thrill-oriented behavior, neuroscientists and sports psychologists have established a link between the level of dopamine produced by the brains of these thrill-seekers and their behavior.

Specifically, these people often come from families made up of individuals who produce higher-than-average dopamine. Dopamine is a brain chemical that acts as a messenger involved in reward, motivation and mood.

Scientists and sports psychologists also note that repetitious practice of a behavior—a thrilling one or not—can lead the brain to establish it as “normal,” and can lead the person repeating the behavior to essentially go into “autopilot.” Coupled with high dopamine levels, this feeling of a risky behavior being routine and “normal” can lead to an increased sense of fearlessness in the people who continuously perform these activities.

Along with incredible skill, these factors combine to make Danica Patrick a speeding success on the racetrack. Even Danica thinks, though, that it all comes down to her genes.

“I think racing is in my blood, my DNA,” she said.


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